The ‘entourage effect’ is a new term coined to describe the idea that all compounds found in the cannabis plant work synergistically, providing more benefit together than the individual compounds would provide alone. The earliest evidence of its medicinal use dates back to 2700 BC when Chinese Emperor Shen Nung documented the analgesic (pain-relieving) properties.
- Viola Brugnatelli is a Neuroscientist specialised in Cannabinoid circuitry & GPCRs signalling.
- Her academy and research training let her gain extensive experience on medical cannabis and terpenes both from preclinical as well as clinical perspective.
- A recent epidemiological study reported that 71.7% of cannabis patients described significant improvements of their condition after only 1 month of cannabis therapy, to reach 92% overall improvements after 2 months.
- Sorry, at this time CBD products cannot be shipped outside of the US.
Shen Nung is considered by many to be the father of Chinese medicine, which has helped to heal people through the use of natural remedies for thousands of years. Cannabis has been used as a plant medicine for the treatment of an impressively wide array of diseases.
With the legality of marijuana spreading across the United States and other countries, many people are now being given the opportunity to switch from dangerous, addictive medications to a natural, safer alternative. Do not operate a vehicle or heavy machinery under the influence of cannabis. CBD oils, on the other hand, are usually taken in a capsule or sublingually, but they, too, can be administered any number of ways.
CBD is the second most well-known cannabinoid found in cannabis, and like most of the other phytocannabinoids, it is non-psychotropic. THC is the psychotropic phytocannabinoid that is to thank for the “high” effect users get when they smoke weed. It has been found to have a variety of health-related benefits for the user.
CBD has been found to exhibit enhancements in treating pain both when used on its own and when used in combination with THC. When used alone, CBD is largely best for inflammatory pain, such as that caused by arthritis or injuries. Using these two compounds in concert has been shown to help mitigate side effects and enhance efficacy, with CBD plus THC showing more benefit for some conditions than THC alone. This research supports the idea that it is best to use the whole cannabis plant, with CBD, THC, and the natural medley of additional compounds. This harmony between the various plant chemicals found in marijuana is colloquially referred to as the entourage effect.
While human studies have found benefits from the use of THC, CBD, and whole-plant marijuana in relieving pain, much of the evidence for this use comes from user reports and surveys. CBD does not directly bind to the receptors found in the endocannabinoid system but rather works to modulate the effects of the endocannabinoids as well as working as a CB1 receptor antagonist.
That said, the research conducted thus far, along with countless user reports, suggests that CBD itself may be able to help relieve pain. StrainCategoryCBD ContentTHC ContentDescriptionACDCHybridHighLowProduces no noticeable high feeling due to very low THC content. Lastly, there are countless user reports on specific strains of weed that have been found to be powerful for relieving pain. While some of these strains are high CBD, indica strains, some strains of weed used for pain do not fall into this category. While this is not an exact science, users tend to report more effective pain-relieving properties with indicas.
In one survey, participants reported that indicas helped more than sativas when it came to headaches, joint pain, neuropathy, and spasticity. Users also reported indicas to be more helpful when it comes to sleep and sedation. There are a few things that you will want to consider outside of simple percentage CBD and THC. One of these considerations is the ‘type’ of cannabis you are purchasing.